منابع مشابه
Ontogeny and homeostasis of Langerhans cells.
Langerhans cells (LCs) refer to the dendritic cells (DCs) that populate the epidermis. Strategically located at one of the body's largest interfaces with the external environment, they form the first line of defense against pathogens that breach the skin. Although LCs share several phenotypical and functional features with lymphoid and non-lymphoid organ DCs, they also have unique properties th...
متن کاملLangerhans Cells in Skin Lesions of Leprosy
Background: Langerhans cells are important in the pathogenesis of leprosy. A recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. Objective: To investigate a possible relationship between the number of Langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. Methods: An immunohistochemical staining for S100 prot...
متن کاملOntogeny of Myeloid Cells
Granulocytes, monocytes, macrophages, and dendritic cells (DCs) represent a subgroup of leukocytes, collectively called myeloid cells. During the embryonic development of mammalians, myelopoiesis occurs in a stepwise fashion that begins in the yolk sac and ends up in the bone marrow (BM). During this process, these early monocyte progenitors colonize various organs such as the brain, liver, ski...
متن کاملDifferentiation of Langerhans cells in Langerhans cell histiocytosis.
Langerhans cell histiocytosis (LCH) consists of lesions composed of cells with a dendritic Langerhans cell (LC) phenotype. The clinical course of LCH ranges from spontaneous resolution to a chronic and sometimes lethal disease. We studied 25 patients with various clinical forms of the disease. In bone and chronic lesions, LCH cells had immature phenotype and function. They coexpressed LC antige...
متن کاملlangerhans cells in skin lesions of leprosy
background: langerhans cells are important in the pathogenesis of leprosy. a recent study reported that these cells were almost absent in the epidermis overlying lepromatous lesions. objective: to investigate a possible relationship between the number of langerhans cells and the histopathologic spectrum of lesions in patients with leprosy. methods: an immunohistochemical staining for s100 ...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 1980
ISSN: 0022-202X
DOI: 10.1111/1523-1747.ep12521037